Effect of cancer-associated mutations in the PlexinB1 gene

BACKGROUND: Semaphorins act as chemotactic cues for cell movement via their transmembrane receptors, plexins. Somatic missense mutations in the plexinB1 gene coupled with overexpression of the protein frequently occur in prostate tumours, indicating a role for plexinB1 in the pathogenesis of prostat...

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Detalles Bibliográficos
Autores principales: Zhou, Chun, Wong, Oscar Gee-Wan, Masters, John R, Williamson, Magali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3317836/
https://www.ncbi.nlm.nih.gov/pubmed/22404908
http://dx.doi.org/10.1186/1476-4598-11-11

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