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Cytoneme-Mediated Delivery of Hedgehog Regulates the Expression of Bone Morphogenetic Proteins to Maintain Germline Stem Cells in Drosophila

Stem cells reside in specialised microenvironments, or niches, which often contain support cells that control stem cell maintenance and proliferation. Hedgehog (Hh) proteins mediate homeostasis in several adult niches, but a detailed understanding of Hh signalling in stem cell regulation is lacking....

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Detalles Bibliográficos
Autores principales: Rojas-Ríos, Patricia, Guerrero, Isabel, González-Reyes, Acaimo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3317903/
https://www.ncbi.nlm.nih.gov/pubmed/22509132
http://dx.doi.org/10.1371/journal.pbio.1001298