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In Situ Monitoring of Intracellular Glucose and Glutamine in CHO Cell Culture
The development of processes to produce biopharmaceuticals industrially is still largely empirical and relies on optimizing both medium formulation and cell line in a product-specific manner. Current small-scale (well plate-based) process development methods cannot provide sufficient sample volume f...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3317985/ https://www.ncbi.nlm.nih.gov/pubmed/22509313 http://dx.doi.org/10.1371/journal.pone.0034512 |