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RLIP76 Regulates PI3K/Akt Signaling and Chemo-Radiotherapy Resistance in Pancreatic Cancer

PURPOSE: Pancreatic cancer is an aggressive malignancy with characteristic metastatic course of disease and resistance to conventional chemo-radiotherapy. RLIP76 is a multi-functional cell membrane protein that functions as a major mercapturic acid pathway transporter as well as key regulator of rec...

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Detalles Bibliográficos
Autores principales: Leake, Kathryn, Singhal, Jyotsana, Nagaprashantha, Lokesh Dalasanur, Awasthi, Sanjay, Singhal, Sharad S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3317991/
https://www.ncbi.nlm.nih.gov/pubmed/22509328
http://dx.doi.org/10.1371/journal.pone.0034582