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Characterisation of the contribution of the GABA-benzodiazepine α1 receptor subtype to [(11)C]Ro15-4513 PET images

This positron emission tomography (PET) study aimed to further define selectivity of [(11)C]Ro15-4513 binding to the GABARα5 relative to the GABARα1 benzodiazepine receptor subtype. The impact of zolpidem, a GABARα1-selective agonist, on [(11)C]Ro15-4513, which shows selectivity for GABARα5, and the...

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Detalles Bibliográficos
Autores principales: Myers, James FM, Rosso, Lula, Watson, Ben J, Wilson, Sue J, Kalk, Nicola J, Clementi, Nicoletta, Brooks, David J, Nutt, David J, Turkheimer, Federico E, Lingford-Hughes, Anne R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3318150/
https://www.ncbi.nlm.nih.gov/pubmed/22214903
http://dx.doi.org/10.1038/jcbfm.2011.177