Comparative oncology: ErbB-1 and ErbB-2 homologues in canine cancer are susceptible to cetuximab and trastuzumab targeting

To facilitate comparative oncology trials we compared the biological and molecular homologies of canine (dog; Canis lupus familiaris) and human tumor-associated antigens ErbB-1 and -2. Further, we investigated whether they could serve as targets for anti-ErbB-1 (cetuximab) and anti-ErbB-2 antibodies...

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Detalles Bibliográficos
Autores principales: Singer, Josef, Weichselbaumer, Marlene, Stockner, Thomas, Mechtcheriakova, Diana, Sobanov, Yury, Bajna, Erika, Wrba, Friedrich, Horvat, Reinhard, Thalhammer, Johann G., Willmann, Michael, Jensen-Jarolim, Erika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pergamon Press 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3318186/
https://www.ncbi.nlm.nih.gov/pubmed/22424313
http://dx.doi.org/10.1016/j.molimm.2012.01.002

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