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Impact of Novel Resistance Profiles in HIV-1 Reverse Transcriptase on Phenotypic Resistance to NVP
Objective. To clarify the impact of H221Y mutation on drug resistance to NVP. Methods. 646 bp HIV-1 pol gene fragments (from 592 to 1237 nucleotide) with different NNRTIs mutation profiles from AIDS patients receiving antiretroviral therapy containing NVP regimens were introduced into pNL4-3 backbon...
Autores principales: | Jiao, Liyan, Li, Hanping, Li, Lin, Zhuang, Daomin, Liu, Yongjian, Bao, Zuoyi, Liu, Siyang, Li, Jingyun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3318213/ https://www.ncbi.nlm.nih.gov/pubmed/22536497 http://dx.doi.org/10.1155/2012/637263 |
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