The Stochastic Evolution of a Protocell: The Gillespie Algorithm in a Dynamically Varying Volume

We propose an improvement of the Gillespie algorithm allowing us to study the time evolution of an ensemble of chemical reactions occurring in a varying volume, whose growth is directly related to the amount of some specific molecules, belonging to the reactions set. This allows us to study the stoc...

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Detalles Bibliográficos
Autores principales: Carletti, T., Filisetti, A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3318221/
https://www.ncbi.nlm.nih.gov/pubmed/22536297
http://dx.doi.org/10.1155/2012/423627
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author Carletti, T.
Filisetti, A.
author_facet Carletti, T.
Filisetti, A.
author_sort Carletti, T.
collection PubMed
description We propose an improvement of the Gillespie algorithm allowing us to study the time evolution of an ensemble of chemical reactions occurring in a varying volume, whose growth is directly related to the amount of some specific molecules, belonging to the reactions set. This allows us to study the stochastic evolution of a protocell, whose volume increases because of the production of container molecules. Several protocell models are considered and compared with the deterministic models.
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spelling pubmed-33182212012-04-25 The Stochastic Evolution of a Protocell: The Gillespie Algorithm in a Dynamically Varying Volume Carletti, T. Filisetti, A. Comput Math Methods Med Research Article We propose an improvement of the Gillespie algorithm allowing us to study the time evolution of an ensemble of chemical reactions occurring in a varying volume, whose growth is directly related to the amount of some specific molecules, belonging to the reactions set. This allows us to study the stochastic evolution of a protocell, whose volume increases because of the production of container molecules. Several protocell models are considered and compared with the deterministic models. Hindawi Publishing Corporation 2012 2012-03-07 /pmc/articles/PMC3318221/ /pubmed/22536297 http://dx.doi.org/10.1155/2012/423627 Text en Copyright © 2012 T. Carletti and A. Filisetti. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Carletti, T.
Filisetti, A.
The Stochastic Evolution of a Protocell: The Gillespie Algorithm in a Dynamically Varying Volume
title The Stochastic Evolution of a Protocell: The Gillespie Algorithm in a Dynamically Varying Volume
title_full The Stochastic Evolution of a Protocell: The Gillespie Algorithm in a Dynamically Varying Volume
title_fullStr The Stochastic Evolution of a Protocell: The Gillespie Algorithm in a Dynamically Varying Volume
title_full_unstemmed The Stochastic Evolution of a Protocell: The Gillespie Algorithm in a Dynamically Varying Volume
title_short The Stochastic Evolution of a Protocell: The Gillespie Algorithm in a Dynamically Varying Volume
title_sort stochastic evolution of a protocell: the gillespie algorithm in a dynamically varying volume
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3318221/
https://www.ncbi.nlm.nih.gov/pubmed/22536297
http://dx.doi.org/10.1155/2012/423627
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