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Elucidation and Chemical Modulation of Sulfolipid-1 Biosynthesis in Mycobacterium tuberculosis
Mycobacterium tuberculosis possesses unique cell-surface lipids that have been implicated in virulence. One of the most abundant is sulfolipid-1 (SL-1), a tetraacyl-sulfotrehalose glycolipid. Although the early steps in SL-1 biosynthesis are known, the machinery underlying the final acylation reacti...
Autores principales: | Seeliger, Jessica C., Holsclaw, Cynthia M., Schelle, Michael W., Botyanszki, Zsofia, Gilmore, Sarah A., Tully, Sarah E., Niederweis, Michael, Cravatt, Benjamin F., Leary, Julie A., Bertozzi, Carolyn R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3318749/ https://www.ncbi.nlm.nih.gov/pubmed/22194604 http://dx.doi.org/10.1074/jbc.M111.315473 |
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