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Mineralocorticoid Receptor Blocker Protects against Podocyte-Dependent Glomerulosclerosis
BACKGROUND: We previously showed that angiotensin type 1 receptor (AT1) blocker (ARB) attenuates glomerular injury in Nphs1-hCD25 (NEP25) transgenic mice, a model of selective podocyte injury. However, subsequent studies in NEP25 mice with podocyte-specific deficiency of AT1 revealed that the protec...
Autores principales: | Takagi, Nobuaki, Tanizawa, Takakuni, Kon, Valentina, Fogo, Agnes B., Ichikawa, Iekuni, Ma, Ji |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
S. Karger AG
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3318935/ https://www.ncbi.nlm.nih.gov/pubmed/22479265 http://dx.doi.org/10.1159/000334961 |
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