Factors Associated with a Depressive Disorder in Alzheimer's Disease Are Different from Those Found for Other Dementia Disorders

BACKGROUND: This study explores factors associated with depression in Alzheimer's disease (AD) compared with mild cognitive impairment (MCI) and other dementia disorders. METHOD: In a prospective study we included 195 patients: 31 with MCI, 112 with AD and 52 with other dementias. RESULTS: Acco...

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Detalles Bibliográficos
Autores principales: Barca, Maria Lage, Engedal, Knut, Laks, Jerson, Selbaek, Geir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2012
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3318937/
https://www.ncbi.nlm.nih.gov/pubmed/22479262
http://dx.doi.org/10.1159/000335775
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author Barca, Maria Lage
Engedal, Knut
Laks, Jerson
Selbaek, Geir
author_facet Barca, Maria Lage
Engedal, Knut
Laks, Jerson
Selbaek, Geir
author_sort Barca, Maria Lage
collection PubMed
description BACKGROUND: This study explores factors associated with depression in Alzheimer's disease (AD) compared with mild cognitive impairment (MCI) and other dementia disorders. METHOD: In a prospective study we included 195 patients: 31 with MCI, 112 with AD and 52 with other dementias. RESULTS: According to the ICD-10 and the DSM-IV criteria, 88 (44.1%) and 59 (30.3%), respectively, had a depressive disorder. An adjusted multiple regression analysis showed that previous depression (p < 0.05) was significantly associated with depression in AD patients. Severity of dementia (p < 0.05) was significantly associated with a depressive disorder in a group of patients with frontotemporal dementia, vascular dementia, or dementia due to Lewy Body disease or Parkinson's disease. CONCLUSION: We found different factors associated with a depressive disorder in AD compared to those found for other dementia disorders.
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spelling pubmed-33189372012-04-04 Factors Associated with a Depressive Disorder in Alzheimer's Disease Are Different from Those Found for Other Dementia Disorders Barca, Maria Lage Engedal, Knut Laks, Jerson Selbaek, Geir Dement Geriatr Cogn Dis Extra Original Research Article BACKGROUND: This study explores factors associated with depression in Alzheimer's disease (AD) compared with mild cognitive impairment (MCI) and other dementia disorders. METHOD: In a prospective study we included 195 patients: 31 with MCI, 112 with AD and 52 with other dementias. RESULTS: According to the ICD-10 and the DSM-IV criteria, 88 (44.1%) and 59 (30.3%), respectively, had a depressive disorder. An adjusted multiple regression analysis showed that previous depression (p < 0.05) was significantly associated with depression in AD patients. Severity of dementia (p < 0.05) was significantly associated with a depressive disorder in a group of patients with frontotemporal dementia, vascular dementia, or dementia due to Lewy Body disease or Parkinson's disease. CONCLUSION: We found different factors associated with a depressive disorder in AD compared to those found for other dementia disorders. S. Karger AG 2012-02-03 /pmc/articles/PMC3318937/ /pubmed/22479262 http://dx.doi.org/10.1159/000335775 Text en Copyright © 2012 by S. Karger AG, Basel http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-Noncommercial-No-Derivative-Works License (http://creativecommons.org/licenses/by-nc-nd/3.0/). Users may download, print and share this work on the Internet for noncommercial purposes only, provided the original work is properly cited, and a link to the original work on http://www.karger.com and the terms of this license are included in any shared versions.
spellingShingle Original Research Article
Barca, Maria Lage
Engedal, Knut
Laks, Jerson
Selbaek, Geir
Factors Associated with a Depressive Disorder in Alzheimer's Disease Are Different from Those Found for Other Dementia Disorders
title Factors Associated with a Depressive Disorder in Alzheimer's Disease Are Different from Those Found for Other Dementia Disorders
title_full Factors Associated with a Depressive Disorder in Alzheimer's Disease Are Different from Those Found for Other Dementia Disorders
title_fullStr Factors Associated with a Depressive Disorder in Alzheimer's Disease Are Different from Those Found for Other Dementia Disorders
title_full_unstemmed Factors Associated with a Depressive Disorder in Alzheimer's Disease Are Different from Those Found for Other Dementia Disorders
title_short Factors Associated with a Depressive Disorder in Alzheimer's Disease Are Different from Those Found for Other Dementia Disorders
title_sort factors associated with a depressive disorder in alzheimer's disease are different from those found for other dementia disorders
topic Original Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3318937/
https://www.ncbi.nlm.nih.gov/pubmed/22479262
http://dx.doi.org/10.1159/000335775
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