Homeostatic control of recombination is implemented progressively in mouse meiosis

Humans suffer from high rates of fetal aneuploidy, often arising from the absence of meiotic crossover recombination between homologous chromosomes(1). Meiotic recombination is initiated by double-strand breaks (DSBs) generated by the SPO11 transesterase(2). In yeast and worms, at least one bufferin...

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Detalles Bibliográficos
Autores principales: Cole, Francesca, Kauppi, Liisa, Lange, Julian, Roig, Ignasi, Wang, Raymond, Keeney, Scott, Jasin, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3319518/
https://www.ncbi.nlm.nih.gov/pubmed/22388890
http://dx.doi.org/10.1038/ncb2451

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3319518/
https://www.ncbi.nlm.nih.gov/pubmed/22388890
http://dx.doi.org/10.1038/ncb2451

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