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Homeostatic control of recombination is implemented progressively in mouse meiosis
Humans suffer from high rates of fetal aneuploidy, often arising from the absence of meiotic crossover recombination between homologous chromosomes(1). Meiotic recombination is initiated by double-strand breaks (DSBs) generated by the SPO11 transesterase(2). In yeast and worms, at least one bufferin...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3319518/ https://www.ncbi.nlm.nih.gov/pubmed/22388890 http://dx.doi.org/10.1038/ncb2451 |