Fast Homozygosity Mapping and Identification of a Zebrafish ENU-Induced Mutation by Whole-Genome Sequencing

Forward genetics using zebrafish is a powerful tool for studying vertebrate development through large-scale mutagenesis. Nonetheless, the identification of the molecular lesion is still laborious and involves time-consuming genetic mapping. Here, we show that high-throughput sequencing of the whole...

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Detalles Bibliográficos
Autores principales: Voz, Marianne L., Coppieters, Wouter, Manfroid, Isabelle, Baudhuin, Ariane, Von Berg, Virginie, Charlier, Carole, Meyer, Dirk, Driever, Wolfgang, Martial, Joseph A., Peers, Bernard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3319596/
https://www.ncbi.nlm.nih.gov/pubmed/22496837
http://dx.doi.org/10.1371/journal.pone.0034671

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