Cargando…

Macrophage-Associated Mesenchymal Stem Cells Assume an Activated, Migratory, Pro-Inflammatory Phenotype with Increased IL-6 and CXCL10 Secretion

Mesenchymal stem cells (MSCs) exhibit tropism for sites of tissue injury and tumors. However, the influence of the microenvironment on MSC phenotype and localization remains incompletely characterized. In this study, we begin to define a macrophage-induced MSC phenotype. These MSCs secrete interleuk...

Descripción completa

Detalles Bibliográficos
Autores principales:	Anton, Kevin, Banerjee, Debabrata, Glod, John
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3319627/ https://www.ncbi.nlm.nih.gov/pubmed/22496888 http://dx.doi.org/10.1371/journal.pone.0035036

Ejemplares similares

Differentiated fibrocytes assume a functional mesenchymal phenotype with regenerative potential
por: Ling, Changying, et al.
Publicado: (2019)

P53 regulates the migration of mesenchymal stromal cells in response to the tumor microenvironment through both CXCL12-dependent and -independent mechanisms
por: LIN, SIANG-YO, et al.
Publicado: (2013)

Bone marrow mesenchymal stem cells can differentiate and assume corneal keratocyte phenotype
por: Liu, Hongshan, et al.
Publicado: (2012)

RNA-seq of macrophages of amoeboid or mesenchymal migratory phenotype due to specific structure of environment
por: Čermák, Vladimír, et al.
Publicado: (2018)

Expression and Secretion of CXCL-8 and CXCL-10 From Mycobacterium Bovis BCG-Infected Human Epithelial Cells: Role of IL-4
por: Méndez-Samperio, Patricia, et al.
Publicado: (2006)

Pathogenic Roles of CXCL10 in Experimental Autoimmune Prostatitis by Modulating Macrophage Chemotaxis and Cytokine Secretion
por: Hua, Xiaoliang, et al.
Publicado: (2021)

Tumor-Activated Mesenchymal Stromal Cells Promote Osteosarcoma Stemness and Migratory Potential via IL-6 Secretion
por: Cortini, Margherita, et al.
Publicado: (2016)

Macrophage Phenotype Modulation by CXCL4 in Atherosclerosis
por: Gleissner, Christian A.
Publicado: (2012)

CCL2 and CXCL12 Derived from Mesenchymal Stromal Cells Cooperatively Polarize IL-10+ Tissue Macrophages to Mitigate Gut Injury
por: Giri, Jayeeta, et al.
Publicado: (2020)

Infiltration by CXCL10 Secreting Macrophages Is Associated With Antitumor Immunity and Response to Therapy in Ovarian Cancer Subtypes
por: Ardighieri, Laura, et al.
Publicado: (2021)

Pro-inflammatory CXCL-10, TNF-α, IL-1β, and IL-6: biomarkers of SARS-CoV-2 infection
por: Tripathy, Anuradha S., et al.
Publicado: (2021)

IL-10 Promotes CXCL13 Expression in Macrophages Following Foot-and-Mouth Disease Virus Infection
por: Guo, Zijing, et al.
Publicado: (2023)

Seminal Levels of Pro-inflammatory (CXCL1, CXCL9, CXCL10) and Homeostatic (CXCL12) Chemokines in Men With Asymptomatic Chlamydia trachomatis Infection
por: Hakimi, Hamid, et al.
Publicado: (2014)

Umbilical Cord-derived Mesenchymal Stem Cells Instruct Monocytes Towards an IL10-producing Phenotype by Secreting IL6 and HGF
por: Deng, Yinan, et al.
Publicado: (2016)

Expression and migratory analysis of 5 human uveal melanoma cell lines for CXCL12, CXCL8, CXCL1, and HGF
por: Di Cesare, Sebastian, et al.
Publicado: (2007)

Assume, Guarantee or Repair
por: Frenkel, Hadar, et al.
Publicado: (2020)

Human integrin α10β1-selected mesenchymal stem cells home to cartilage defects in the rabbit knee and assume a chondrocyte-like phenotype
por: Andersen, Camilla, et al.
Publicado: (2022)

Immunomodulation of CXCL10 Secretion by Hepatitis C Virus: Could CXCL10 Be a Prognostic Marker of Chronic Hepatitis C?
por: Ferrari, Silvia Martina, et al.
Publicado: (2019)

Coexpression and interaction of CXCL10 and CD26 in mesenchymal cells by synergising inflammatory cytokines: CXCL8 and CXCL10 are discriminative markers for autoimmune arthropathies
por: Proost, Paul, et al.
Publicado: (2006)

The chemokines IP-10/CXCL10 and IL-8/CXCL8 are potential novel biomarkers of warm autoimmune hemolytic anemia
por: Branch, Donald R., et al.
Publicado: (2022)

Macrophages induce differentiation of plasma cells through CXCL10/IP-10
por: Xu, Wei, et al.
Publicado: (2012)

The Pro-Inflammatory Chemokines CXCL9, CXCL10 and CXCL11 Are Upregulated Following SARS-CoV-2 Infection in an AKT-Dependent Manner
por: Callahan, Victoria, et al.
Publicado: (2021)

Spatially resolved transcriptomics reveals pro-inflammatory fibroblast involved in lymphocyte recruitment through CXCL8 and CXCL10
por: Caetano, Ana J, et al.
Publicado: (2023)

Ovaries Secrete Male Hormone: VI. A Preliminary Note on the Possibilities of Androgen-secreting Ovaries to Assume an Adrenal Function
por: Hill, R. T.
Publicado: (1944)

IL-17-differentiated macrophages secrete pro-inflammatory cytokines in response to oxidized low-density lipoprotein
por: de la Paz Sánchez-Martínez, María, et al.
Publicado: (2017)

Pro-pigmentary action of 5-fluorouracil through the stimulated secretion of CXCL12 by dermal fibroblasts
por: Liao, Zhi-Kai, et al.
Publicado: (2021)

Epinephrine stimulates CXCL1 IL‐1α, IL‐6 secretion in isolated mouse limb muscle
por: Mattingly, Alex J., et al.
Publicado: (2017)

The Effect of Secreted IL-10 from Mesenchymal Stem Cell on Immune Checkpoint Molecules
por: Sari, Mutiara Indah, et al.
Publicado: (2023)

Widely assumed phenotypic associations in Cannabis sativa lack a shared genetic basis
por: Vergara, Daniela, et al.
Publicado: (2021)

Is CERN Council assuming its responsibilities?
por: Association du personnel, et al.
Publicado: (2008)

Adenovirus-engineered human dendritic cells induce natural killer cell chemotaxis via CXCL8/IL-8 and CXCL10/IP-10
por: Vujanovic, Lazar, et al.
Publicado: (2012)

Role of TNF α, IL-6 and CXCL10 in Dengue disease severity
por: Masood, Kiran Iqbal, et al.
Publicado: (2018)

Combined Detection of Serum IL-10, IL-17, and CXCL10 Predicts Acute Rejection Following Adult Liver Transplantation
por: Kim, Nayoung, et al.
Publicado: (2016)

Cowpox virus but not Vaccinia virus induces secretion of CXCL1, IL-8 and IL-6 and chemotaxis of monocytes in vitro
por: Bourquain, Daniel, et al.
Publicado: (2013)

Dysregulated expression of MIG/CXCL9, IP-10/CXCL10 and CXCL16 and their receptors in systemic sclerosis
por: Rabquer, Bradley J, et al.
Publicado: (2011)

The Secretome of Preconditioned Mesenchymal Stem Cells Drives Polarization and Reprogramming of M2a Macrophages toward an IL-10-Producing Phenotype
por: Holthaus, Michelle, et al.
Publicado: (2022)

MLKL signaling regulates macrophage polarization in acute pancreatitis through CXCL10
por: Peng, Cheng, et al.
Publicado: (2023)

The antiviral protein viperin regulates chondrogenic differentiation via CXCL10 protein secretion
por: Steinbusch, Mandy M. F., et al.
Publicado: (2019)

IL-10-providing B cells govern pro-inflammatory activity of macrophages and microglia in CNS autoimmunity
por: Geladaris, Anastasia, et al.
Publicado: (2023)

Dynamic model assuming mutually inhibitory biomarkers of frailty suggests bistability with contrasting mobility phenotypes
por: Schaumburger, Nathan, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_kgfmcdq2uo1nadvhj73furhv24