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Predictors of Metabolic Syndrome in Participants of a Cardiac Rehabilitation Program

Metabolic syndrome increases the risk of all-cause mortality, cardiovascular mortality and cardiovascular events in patients with cardiovascular disease (CVD). This study assessed the predictors of metabolic syndrome, both its incidence and resolution in a cohort of cardiac rehabilitation program gr...

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Autores principales: Farias Godoy, Alejandra, Ignaszewski, Andrew, Frohlich, Jiri, Lear, Scott A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scholarly Research Network 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3319994/
https://www.ncbi.nlm.nih.gov/pubmed/22536528
http://dx.doi.org/10.5402/2012/736314
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author Farias Godoy, Alejandra
Ignaszewski, Andrew
Frohlich, Jiri
Lear, Scott A.
author_facet Farias Godoy, Alejandra
Ignaszewski, Andrew
Frohlich, Jiri
Lear, Scott A.
author_sort Farias Godoy, Alejandra
collection PubMed
description Metabolic syndrome increases the risk of all-cause mortality, cardiovascular mortality and cardiovascular events in patients with cardiovascular disease (CVD). This study assessed the predictors of metabolic syndrome, both its incidence and resolution in a cohort of cardiac rehabilitation program graduates. Methods. A total of 154 and 80 participants without and with metabolic syndrome respectively were followed for 48 months. Anthropometric measurements, metabolic risk factors, and quality of life were assessed at baseline and at 48 months. Logistic regression models were used to assess the predictors of metabolic syndrome onset and resolution. Results. Increasing waist circumference (OR 1.175, P ≤ 0.001) was an independent predictor for incident metabolic syndrome (R (2) for model = 0.46). Increasing waist circumference (OR 1.234, P ≤ 0.001), decreasing HDL-C (OR 0.027, P = 0.005), and increasing triglycerides (OR 3.005, P = 0.003) were predictors of metabolic syndrome resolution. Conclusion. Patients with CVD that further develop metabolic syndrome are particularly susceptible for the cascade of cardiovascular events and mortality. Increasing waist circumference confers a higher risk for future onset of metabolic syndrome in this group of patients. They will require closer follow-up and should be targeted for further prevention strategies after cardiac rehabilitation program completion.
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spelling pubmed-33199942012-04-25 Predictors of Metabolic Syndrome in Participants of a Cardiac Rehabilitation Program Farias Godoy, Alejandra Ignaszewski, Andrew Frohlich, Jiri Lear, Scott A. ISRN Cardiol Clinical Study Metabolic syndrome increases the risk of all-cause mortality, cardiovascular mortality and cardiovascular events in patients with cardiovascular disease (CVD). This study assessed the predictors of metabolic syndrome, both its incidence and resolution in a cohort of cardiac rehabilitation program graduates. Methods. A total of 154 and 80 participants without and with metabolic syndrome respectively were followed for 48 months. Anthropometric measurements, metabolic risk factors, and quality of life were assessed at baseline and at 48 months. Logistic regression models were used to assess the predictors of metabolic syndrome onset and resolution. Results. Increasing waist circumference (OR 1.175, P ≤ 0.001) was an independent predictor for incident metabolic syndrome (R (2) for model = 0.46). Increasing waist circumference (OR 1.234, P ≤ 0.001), decreasing HDL-C (OR 0.027, P = 0.005), and increasing triglycerides (OR 3.005, P = 0.003) were predictors of metabolic syndrome resolution. Conclusion. Patients with CVD that further develop metabolic syndrome are particularly susceptible for the cascade of cardiovascular events and mortality. Increasing waist circumference confers a higher risk for future onset of metabolic syndrome in this group of patients. They will require closer follow-up and should be targeted for further prevention strategies after cardiac rehabilitation program completion. International Scholarly Research Network 2012-03-28 /pmc/articles/PMC3319994/ /pubmed/22536528 http://dx.doi.org/10.5402/2012/736314 Text en Copyright © 2012 Alejandra Farias Godoy et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Clinical Study
Farias Godoy, Alejandra
Ignaszewski, Andrew
Frohlich, Jiri
Lear, Scott A.
Predictors of Metabolic Syndrome in Participants of a Cardiac Rehabilitation Program
title Predictors of Metabolic Syndrome in Participants of a Cardiac Rehabilitation Program
title_full Predictors of Metabolic Syndrome in Participants of a Cardiac Rehabilitation Program
title_fullStr Predictors of Metabolic Syndrome in Participants of a Cardiac Rehabilitation Program
title_full_unstemmed Predictors of Metabolic Syndrome in Participants of a Cardiac Rehabilitation Program
title_short Predictors of Metabolic Syndrome in Participants of a Cardiac Rehabilitation Program
title_sort predictors of metabolic syndrome in participants of a cardiac rehabilitation program
topic Clinical Study
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3319994/
https://www.ncbi.nlm.nih.gov/pubmed/22536528
http://dx.doi.org/10.5402/2012/736314
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