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The Efficacy of Gelam Honey Dressing towards Excisional Wound Healing
Honey is one of the oldest substances used in wound management. Efficacy of Gelam honey in wound healing was evaluated in this paper. Sprague-Dawley rats were randomly divided into four groups of 24 rats each (untreated group, saline group, Intrasite Gel group, and Gelam honey group) with 2 cm by 2 ...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3320037/ https://www.ncbi.nlm.nih.gov/pubmed/22536292 http://dx.doi.org/10.1155/2012/805932 |
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author | Tan, Mui Koon Hasan Adli, Durriyyah Sharifah Tumiran, Mohd Amzari Abdulla, Mahmood Ameen Yusoff, Kamaruddin Mohd |
author_facet | Tan, Mui Koon Hasan Adli, Durriyyah Sharifah Tumiran, Mohd Amzari Abdulla, Mahmood Ameen Yusoff, Kamaruddin Mohd |
author_sort | Tan, Mui Koon |
collection | PubMed |
description | Honey is one of the oldest substances used in wound management. Efficacy of Gelam honey in wound healing was evaluated in this paper. Sprague-Dawley rats were randomly divided into four groups of 24 rats each (untreated group, saline group, Intrasite Gel group, and Gelam honey group) with 2 cm by 2 cm full thickness, excisional wound created on neck area. Wounds were dressed topically according to groups. Rats were sacrificed on days 1, 5, 10, and 15 of treatments. Wounds were then processed for macroscopic and histological observations. Gelam-honey-dressed wounds healed earlier (day 13) than untreated and saline treated groups, as did wounds treated with Intrasite Gel. Honey-treated wounds exhibited less scab and only thin scar formations. Histological features demonstrated positive effects of Gelam honey on the wounds. This paper showed that Gelam honey dressing on excisional wound accelerated the process of wound healing. |
format | Online Article Text |
id | pubmed-3320037 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-33200372012-04-25 The Efficacy of Gelam Honey Dressing towards Excisional Wound Healing Tan, Mui Koon Hasan Adli, Durriyyah Sharifah Tumiran, Mohd Amzari Abdulla, Mahmood Ameen Yusoff, Kamaruddin Mohd Evid Based Complement Alternat Med Research Article Honey is one of the oldest substances used in wound management. Efficacy of Gelam honey in wound healing was evaluated in this paper. Sprague-Dawley rats were randomly divided into four groups of 24 rats each (untreated group, saline group, Intrasite Gel group, and Gelam honey group) with 2 cm by 2 cm full thickness, excisional wound created on neck area. Wounds were dressed topically according to groups. Rats were sacrificed on days 1, 5, 10, and 15 of treatments. Wounds were then processed for macroscopic and histological observations. Gelam-honey-dressed wounds healed earlier (day 13) than untreated and saline treated groups, as did wounds treated with Intrasite Gel. Honey-treated wounds exhibited less scab and only thin scar formations. Histological features demonstrated positive effects of Gelam honey on the wounds. This paper showed that Gelam honey dressing on excisional wound accelerated the process of wound healing. Hindawi Publishing Corporation 2012 2012-03-28 /pmc/articles/PMC3320037/ /pubmed/22536292 http://dx.doi.org/10.1155/2012/805932 Text en Copyright © 2012 Mui Koon Tan et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Tan, Mui Koon Hasan Adli, Durriyyah Sharifah Tumiran, Mohd Amzari Abdulla, Mahmood Ameen Yusoff, Kamaruddin Mohd The Efficacy of Gelam Honey Dressing towards Excisional Wound Healing |
title | The Efficacy of Gelam Honey Dressing towards Excisional Wound Healing |
title_full | The Efficacy of Gelam Honey Dressing towards Excisional Wound Healing |
title_fullStr | The Efficacy of Gelam Honey Dressing towards Excisional Wound Healing |
title_full_unstemmed | The Efficacy of Gelam Honey Dressing towards Excisional Wound Healing |
title_short | The Efficacy of Gelam Honey Dressing towards Excisional Wound Healing |
title_sort | efficacy of gelam honey dressing towards excisional wound healing |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3320037/ https://www.ncbi.nlm.nih.gov/pubmed/22536292 http://dx.doi.org/10.1155/2012/805932 |
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