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Ultrastructural and Immunohistochemical Studies on Uptake and Distribution of FITC-Conjugated PLGA Nanoparticles Administered Intratracheally in Rats

Polylactide-glycolide (PLGA) nanoparticles have been developed as pulmonary drug delivery carriers. To investigate their behavior, small- (d50 = 74 nm) and large-sized (d50 = 250 nm) FITC-conjugated PLGA nanoparticles were intratracheally administered to rats and were traced for 5, 30 and 60 minutes...

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Detalles Bibliográficos
Autores principales:	Hara, Kaori, Tsujimoto, Hiroyuki, Huang, C. C., Kawashima, Yoshiaki, Ando, Rie, Kusuoka, Osamu, Tamura, Kazutoshi, Tsutsumi, Masahiro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Japanese Society of Toxicologic Pathology 2012
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3320153/ https://www.ncbi.nlm.nih.gov/pubmed/22481855 http://dx.doi.org/10.1293/tox.25.19

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