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N -Ethyl- N -Nitrosourea Induces Retinal Photoreceptor Damage in Adult Rats

Seven-week-old male Lewis rats received a single intraperitoneal injection of N-ethyl-N-nitrosourea (ENU) (100, 200, 400 or 600 mg/kg), and retinal damage was evaluated 7 days after the treatment. Sequential morphological features of the retina and retinal DNA damage, as determined by a TUNEL assay...

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Detalles Bibliográficos
Autores principales:	Yoshizawa, Katsuhiko, Sasaki, Tomo, Uehara, Norihisa, Kuro, Maki, Kimura, Ayako, Kinoshita, Yuichi, Miki, Hisanori, Yuri, Takashi, Tsubura, Airo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Japanese Society of Toxicologic Pathology 2012
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3320154/ https://www.ncbi.nlm.nih.gov/pubmed/22481856 http://dx.doi.org/10.1293/tox.25.27

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