Space-Time Cluster Analysis of Invasive Meningococcal Disease

Clusters are recognized when meningococcal cases of the same phenotypic strain (markers: serogroup, serotype, and subtype) occur in spatial and temporal proximity. The incidence of such clusters was compared to the incidence that would be expected by chance by using space-time nearest-neighbor analy...

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Detalles Bibliográficos
Autores principales: Hoebe, Christian J.P.A., de Melker, Hester, Spanjaard, Lodewijk, Dankert, Jacob, Nagelkerke, Nico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2004
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3320315/
https://www.ncbi.nlm.nih.gov/pubmed/15498165
http://dx.doi.org/10.3201/eid1009.030992
Descripción
Sumario:Clusters are recognized when meningococcal cases of the same phenotypic strain (markers: serogroup, serotype, and subtype) occur in spatial and temporal proximity. The incidence of such clusters was compared to the incidence that would be expected by chance by using space-time nearest-neighbor analysis of 4,887 confirmed invasive meningococcal cases identified in the 9-year surveillance period 1993–2001 in the Netherlands. Clustering beyond chance only occurred among the closest neighboring cases (comparable to secondary cases) and was small (3.1%, 95% confidence interval 2.1%–4.1%).

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