Molecular Mechanisms of West Nile Virus Pathogenesis in Brain Cells

We analyzed the response of human glioma cells to West Nile virus infection by investigating host transcriptional changes. Changes in expression of 23 genes showed similarities to those in other neurodegenerative diseases. These changes may be useful as potential biomarkers and elucidate novel mecha...

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Detalles Bibliográficos
Autores principales: Koh, Wee-Lee, Ng, Mah-Lee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2005
Materias:
Dispatch
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3320339/
https://www.ncbi.nlm.nih.gov/pubmed/15829208
http://dx.doi.org/10.3201/eid1104.041076
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author Koh, Wee-Lee
Ng, Mah-Lee
author_facet Koh, Wee-Lee
Ng, Mah-Lee
author_sort Koh, Wee-Lee
collection PubMed
description We analyzed the response of human glioma cells to West Nile virus infection by investigating host transcriptional changes. Changes in expression of 23 genes showed similarities to those in other neurodegenerative diseases. These changes may be useful as potential biomarkers and elucidate novel mechanisms behind the neuropathology of infection with this virus.
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spelling pubmed-33203392012-04-20 Molecular Mechanisms of West Nile Virus Pathogenesis in Brain Cells Koh, Wee-Lee Ng, Mah-Lee Emerg Infect Dis Dispatch We analyzed the response of human glioma cells to West Nile virus infection by investigating host transcriptional changes. Changes in expression of 23 genes showed similarities to those in other neurodegenerative diseases. These changes may be useful as potential biomarkers and elucidate novel mechanisms behind the neuropathology of infection with this virus. Centers for Disease Control and Prevention 2005-04 /pmc/articles/PMC3320339/ /pubmed/15829208 http://dx.doi.org/10.3201/eid1104.041076 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Dispatch
Koh, Wee-Lee
Ng, Mah-Lee
Molecular Mechanisms of West Nile Virus Pathogenesis in Brain Cells
title Molecular Mechanisms of West Nile Virus Pathogenesis in Brain Cells
title_full Molecular Mechanisms of West Nile Virus Pathogenesis in Brain Cells
title_fullStr Molecular Mechanisms of West Nile Virus Pathogenesis in Brain Cells
title_full_unstemmed Molecular Mechanisms of West Nile Virus Pathogenesis in Brain Cells
title_short Molecular Mechanisms of West Nile Virus Pathogenesis in Brain Cells
title_sort molecular mechanisms of west nile virus pathogenesis in brain cells
topic Dispatch
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3320339/
https://www.ncbi.nlm.nih.gov/pubmed/15829208
http://dx.doi.org/10.3201/eid1104.041076
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