Human Herpesviruses 6 and 7 and Central Nervous System Infection in Children(1)

The role and frequency of human herpesviruses (HHV)-6 and -7 in central nervous system (CNS) diseases of children are unclear. Cerebrospinal fluid samples from 245 pediatric patients (median age 43 days), submitted for evaluations of possible sepsis or of neurologic symptoms, were tested for HHV-6 a...

Descripción completa

Detalles Bibliográficos
Autores principales: Ansari, Asad, Li, Shaobing, Abzug, Mark J., Weinberg, Adriana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2004
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3320425/
https://www.ncbi.nlm.nih.gov/pubmed/15496247
http://dx.doi.org/10.3201/eid1008.030788
_version_ 1782228828148465664
author Ansari, Asad
Li, Shaobing
Abzug, Mark J.
Weinberg, Adriana
author_facet Ansari, Asad
Li, Shaobing
Abzug, Mark J.
Weinberg, Adriana
author_sort Ansari, Asad
collection PubMed
description The role and frequency of human herpesviruses (HHV)-6 and -7 in central nervous system (CNS) diseases of children are unclear. Cerebrospinal fluid samples from 245 pediatric patients (median age 43 days), submitted for evaluations of possible sepsis or of neurologic symptoms, were tested for HHV-6 and HHV-7 DNA by polymerase chain reaction. HHV-6 DNA was found in 3 of 245 samples, and HHV-7 was found in 0 of 245 samples. The three patients with HHV-6 DNA were <2 months of age. HHV-6 was likely pathogenic in two patients with meningitis who lacked evidence of another microbiologic cause. HHV-6 and HHV-7 are uncommon causes of CNS infection in children. HHV-6 may occasionally cause meningitis in young infants.
format Online
Article
Text
id pubmed-3320425
institution National Center for Biotechnology Information
language English
publishDate 2004
publisher Centers for Disease Control and Prevention
record_format MEDLINE/PubMed
spelling pubmed-33204252012-04-20 Human Herpesviruses 6 and 7 and Central Nervous System Infection in Children(1) Ansari, Asad Li, Shaobing Abzug, Mark J. Weinberg, Adriana Emerg Infect Dis Research The role and frequency of human herpesviruses (HHV)-6 and -7 in central nervous system (CNS) diseases of children are unclear. Cerebrospinal fluid samples from 245 pediatric patients (median age 43 days), submitted for evaluations of possible sepsis or of neurologic symptoms, were tested for HHV-6 and HHV-7 DNA by polymerase chain reaction. HHV-6 DNA was found in 3 of 245 samples, and HHV-7 was found in 0 of 245 samples. The three patients with HHV-6 DNA were <2 months of age. HHV-6 was likely pathogenic in two patients with meningitis who lacked evidence of another microbiologic cause. HHV-6 and HHV-7 are uncommon causes of CNS infection in children. HHV-6 may occasionally cause meningitis in young infants. Centers for Disease Control and Prevention 2004-08 /pmc/articles/PMC3320425/ /pubmed/15496247 http://dx.doi.org/10.3201/eid1008.030788 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Research
Ansari, Asad
Li, Shaobing
Abzug, Mark J.
Weinberg, Adriana
Human Herpesviruses 6 and 7 and Central Nervous System Infection in Children(1)
title Human Herpesviruses 6 and 7 and Central Nervous System Infection in Children(1)
title_full Human Herpesviruses 6 and 7 and Central Nervous System Infection in Children(1)
title_fullStr Human Herpesviruses 6 and 7 and Central Nervous System Infection in Children(1)
title_full_unstemmed Human Herpesviruses 6 and 7 and Central Nervous System Infection in Children(1)
title_short Human Herpesviruses 6 and 7 and Central Nervous System Infection in Children(1)
title_sort human herpesviruses 6 and 7 and central nervous system infection in children(1)
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3320425/
https://www.ncbi.nlm.nih.gov/pubmed/15496247
http://dx.doi.org/10.3201/eid1008.030788
work_keys_str_mv AT ansariasad humanherpesviruses6and7andcentralnervoussysteminfectioninchildren1
AT lishaobing humanherpesviruses6and7andcentralnervoussysteminfectioninchildren1
AT abzugmarkj humanherpesviruses6and7andcentralnervoussysteminfectioninchildren1
AT weinbergadriana humanherpesviruses6and7andcentralnervoussysteminfectioninchildren1

Ejemplares similares