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ERK/pERK expression and B-raf mutations in colon adenocarcinomas: correlation with clinicopathological characteristics
BACKGROUND: Colorectal (CRC) carcinogenesis through various morphological stages has been linked to several genetic and epigenetic changes. The Raf/MEK/ERK (MAPK) signal transduction cascade is an important mediator of a number of cellular fates. METHODS: In this study, we investigated the presence...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3320554/ https://www.ncbi.nlm.nih.gov/pubmed/22376079 http://dx.doi.org/10.1186/1477-7819-10-47 |