A Molecular Model for the Differential Activation of STAT3 and STAT6 by the Herpesviral Oncoprotein Tip

Constitutive STAT signaling provides growth promoting signals in many forms of malignancy. We performed molecular modeling and molecular dynamics studies of the interaction between the regulatory Src homology 2 (SH2) domains of STAT3 and 6 with phosphorylated peptides of the herpesviral oncoprotein...

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Detalles Bibliográficos
Autores principales: Mazumder, Eman Dey, Jardin, Christophe, Vogel, Benjamin, Heck, Elke, Scholz, Brigitte, Lengenfelder, Doris, Sticht, Heinrich, Ensser, Armin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3320567/
https://www.ncbi.nlm.nih.gov/pubmed/22509288
http://dx.doi.org/10.1371/journal.pone.0034306

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