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RNA-Seq Mapping and Detection of Gene Fusions with a Suffix Array Algorithm
High-throughput RNA sequencing enables quantification of transcripts (both known and novel), exon/exon junctions and fusions of exons from different genes. Discovery of gene fusions–particularly those expressed with low abundance– is a challenge with short- and medium-length sequencing reads. To add...
Autores principales: | Sakarya, Onur, Breu, Heinz, Radovich, Milan, Chen, Yongzhi, Wang, Yulei N., Barbacioru, Catalin, Utiramerur, Sowmi, Whitley, Penn P., Brockman, Joel P., Vatta, Paolo, Zhang, Zheng, Popescu, Liviu, Muller, Matthew W., Kudlingar, Vidya, Garg, Nriti, Li, Chieh-Yuan, Kong, Benjamin S., Bodeau, John P., Nutter, Robert C., Gu, Jian, Bramlett, Kelli S., Ichikawa, Jeffrey K., Hyland, Fiona C., Siddiqui, Asim S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3320572/ https://www.ncbi.nlm.nih.gov/pubmed/22496636 http://dx.doi.org/10.1371/journal.pcbi.1002464 |
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