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Neutrophils Promote Mycobacterial Trehalose Dimycolate-Induced Lung Inflammation via the Mincle Pathway

Trehalose 6,6′-dimycolate (TDM), a cord factor of Mycobacterium tuberculosis (Mtb), is an important regulator of immune responses during Mtb infections. Macrophages recognize TDM through the Mincle receptor and initiate TDM-induced inflammatory responses, leading to lung granuloma formation. Althoug...

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Detalles Bibliográficos
Autores principales:	Lee, Wook-Bin, Kang, Ji-Seon, Yan, Ji-Jing, Lee, Myeong Sup, Jeon, Bo-Young, Cho, Sang-Nae, Kim, Young-Joon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3320589/ https://www.ncbi.nlm.nih.gov/pubmed/22496642 http://dx.doi.org/10.1371/journal.ppat.1002614

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