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Structural Basis of Cytotoxicity Mediated by the Type III Secretion Toxin ExoU from Pseudomonas aeruginosa
The type III secretion system (T3SS) is a complex macromolecular machinery employed by a number of Gram-negative pathogens to inject effectors directly into the cytoplasm of eukaryotic cells. ExoU from the opportunistic pathogen Pseudomonas aeruginosa is one of the most aggressive toxins injected by...
Autores principales: | Gendrin, Claire, Contreras-Martel, Carlos, Bouillot, Stéphanie, Elsen, Sylvie, Lemaire, David, Skoufias, Dimitrios A., Huber, Philippe, Attree, Ina, Dessen, Andréa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3320612/ https://www.ncbi.nlm.nih.gov/pubmed/22496657 http://dx.doi.org/10.1371/journal.ppat.1002637 |
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