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Structural and Functional Analysis of the Symmetrical Type I Restriction Endonuclease R.EcoR124I(NT)
Type I restriction-modification (RM) systems are comprised of two multi-subunit enzymes, the methyltransferase (∼160 kDa), responsible for methylation of DNA, and the restriction endonuclease (∼400 kDa), responsible for DNA cleavage. Both enzymes share a number of subunits. An engineered RM system,...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3320862/ https://www.ncbi.nlm.nih.gov/pubmed/22493743 http://dx.doi.org/10.1371/journal.pone.0035263 |