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Seminal Plasma Accelerates Semen-derived Enhancer of Viral Infection (SEVI) Fibril Formation by the Prostatic Acid Phosphatase (PAP(248–286)) Peptide

Amyloid fibrils contained in semen, known as SEVI, or semen-derived enhancer of viral infection, have been shown to increase the infectivity of HIV dramatically. However, previous work with these fibrils has suggested that extensive time and nonphysiologic levels of agitation are necessary to induce...

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Detalles Bibliográficos
Autores principales: Olsen, Joanna S., DiMaio, John T. M., Doran, Todd M., Brown, Caitlin, Nilsson, Bradley L., Dewhurst, Stephen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3320932/
https://www.ncbi.nlm.nih.gov/pubmed/22354963
http://dx.doi.org/10.1074/jbc.M111.314336