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Suppressive Effects on the Immune Response and Protective Immunity to a JEV DNA Vaccine by Co-administration of a GM-CSF-Expressing Plasmid in Mice
As a potential cytokine adjuvant of DNA vaccines, granulocyte-macrophage colony–stimulating factor (GM-CSF) has received considerable attention due to its essential role in the recruitment of antigen-presenting cells, differentiation and maturation of dendritic cells. However, in our recent study of...
Autores principales: | Chen, Hui, Gao, Na, Fan, Dongying, Wu, Jiangman, Zhu, Junping, Li, Jieqiong, Wang, Juan, Chen, Yanlei, An, Jing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3321030/ https://www.ncbi.nlm.nih.gov/pubmed/22493704 http://dx.doi.org/10.1371/journal.pone.0034602 |
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