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Systems approach identifies HIPK2 as a critical regulator of kidney fibrosis
Kidney fibrosis is a common process that leads to the progression of kidney diseases. We used an integrated computational/experimental systems biology approach to identify upstream protein kinases that regulate gene expression changes in kidneys of HIV-1 transgenic mice (Tg26), which have both tubul...
Autores principales: | Jin, Yuanmeng, Ratnam, Krishna, Chuang, Peter Y., Fan, Ying, Zhong, Yifei, Dai, Yan, Mazloom, Amin, Chen, Edward Y., D'Agati, Vivette, Xiong, Huabao, Ross, Michael, Chen, Nan, Ma'ayan, Avi, He, John Cijiang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3321097/ https://www.ncbi.nlm.nih.gov/pubmed/22406746 http://dx.doi.org/10.1038/nm.2685 |
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