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Stability of Predictors of Mortality after Spinal Cord Injury

OBJECTIVE: To identify the stability of socio-environmental, behavioral, and health predictors of mortality over an eight year time frame. STUDY DESIGN: Cohort study. SETTING: Data were analyzed at a large medical university in the Southeast United States of America (USA). METHODS: Adults with resid...

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Autores principales: Krause, James S., Saunders, Lee L., Zhai, Yusheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3321101/
https://www.ncbi.nlm.nih.gov/pubmed/22231541
http://dx.doi.org/10.1038/sc.2011.158
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author Krause, James S.
Saunders, Lee L.
Zhai, Yusheng
author_facet Krause, James S.
Saunders, Lee L.
Zhai, Yusheng
author_sort Krause, James S.
collection PubMed
description OBJECTIVE: To identify the stability of socio-environmental, behavioral, and health predictors of mortality over an eight year time frame. STUDY DESIGN: Cohort study. SETTING: Data were analyzed at a large medical university in the Southeast United States of America (USA). METHODS: Adults with residual impairment from a spinal cord injury (SCI) who were at least one year post-injury at assessment were recruited through a large specialty hospital in the Southeast USA. 1209 participants were included in the final analysis. A piecewise exponential model with 2 equal time intervals (eight years total) was used to assess the stability of the hazard and the predictors over time. RESULTS: The hazard did significantly change over time, where the hazard in the first time interval was significantly lower than the second. There were no interactions between the socio-environmental, behavior, or health factors and time, although there was a significant interaction between age at injury (a demographic variable) and time. CONCLUSION: These results suggest there is stability in the association between the predictors and mortality, even over an eight year time period. Results reinforce the use of historic variables for prediction of mortality in persons with SCI.
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spelling pubmed-33211012012-10-01 Stability of Predictors of Mortality after Spinal Cord Injury Krause, James S. Saunders, Lee L. Zhai, Yusheng Spinal Cord Article OBJECTIVE: To identify the stability of socio-environmental, behavioral, and health predictors of mortality over an eight year time frame. STUDY DESIGN: Cohort study. SETTING: Data were analyzed at a large medical university in the Southeast United States of America (USA). METHODS: Adults with residual impairment from a spinal cord injury (SCI) who were at least one year post-injury at assessment were recruited through a large specialty hospital in the Southeast USA. 1209 participants were included in the final analysis. A piecewise exponential model with 2 equal time intervals (eight years total) was used to assess the stability of the hazard and the predictors over time. RESULTS: The hazard did significantly change over time, where the hazard in the first time interval was significantly lower than the second. There were no interactions between the socio-environmental, behavior, or health factors and time, although there was a significant interaction between age at injury (a demographic variable) and time. CONCLUSION: These results suggest there is stability in the association between the predictors and mortality, even over an eight year time period. Results reinforce the use of historic variables for prediction of mortality in persons with SCI. 2012-01-10 2012-04 /pmc/articles/PMC3321101/ /pubmed/22231541 http://dx.doi.org/10.1038/sc.2011.158 Text en Users may view, print, copy, download and text and data- mine the content in such documents, for the purposes of academic research, subject always to the full Conditions of use: http://www.nature.com/authors/editorial_policies/license.html#terms
spellingShingle Article
Krause, James S.
Saunders, Lee L.
Zhai, Yusheng
Stability of Predictors of Mortality after Spinal Cord Injury
title Stability of Predictors of Mortality after Spinal Cord Injury
title_full Stability of Predictors of Mortality after Spinal Cord Injury
title_fullStr Stability of Predictors of Mortality after Spinal Cord Injury
title_full_unstemmed Stability of Predictors of Mortality after Spinal Cord Injury
title_short Stability of Predictors of Mortality after Spinal Cord Injury
title_sort stability of predictors of mortality after spinal cord injury
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3321101/
https://www.ncbi.nlm.nih.gov/pubmed/22231541
http://dx.doi.org/10.1038/sc.2011.158
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