Activation of neuronal P2X7 receptor-Pannexin-1 mediates death of enteric neurons during colitis

Inflammatory bowel diseases (IBD) are chronic relapsing and remitting conditions associated with long-term gut dysfunction resulting from alterations to the enteric nervous system and a loss of enteric neurons(1,2). The mechanisms underlying inflammation-induced enteric neuron death are unknown. Her...

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Detalles Bibliográficos
Autores principales: Gulbransen, Brian D., Bashashati, Mohammad, Hirota, Simon A., Gui, Xianyong, Roberts, Jane A., MacDonald, Justin A., Muruve, Daniel A., McKay, Derek M., Beck, Paul L., Mawe, Gary M., Thompson, Roger J., Sharkey, Keith A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3321107/
https://www.ncbi.nlm.nih.gov/pubmed/22426419
http://dx.doi.org/10.1038/nm.2679

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