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Exercise Intensity Modulation of Hepatic Lipid Metabolism
Lipid metabolism in the liver is complex and involves the synthesis and secretion of very low density lipoproteins (VLDL), ketone bodies, and high rates of fatty acid oxidation, synthesis, and esterification. Exercise training induces several changes in lipid metabolism in the liver and affects VLDL...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3321535/ https://www.ncbi.nlm.nih.gov/pubmed/22545209 http://dx.doi.org/10.1155/2012/809576 |
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author | Lira, Fábio S. Carnevali, Luiz C. Zanchi, Nelo E. Santos, Ronaldo VT. Lavoie, Jean Marc Seelaender, Marília |
author_facet | Lira, Fábio S. Carnevali, Luiz C. Zanchi, Nelo E. Santos, Ronaldo VT. Lavoie, Jean Marc Seelaender, Marília |
author_sort | Lira, Fábio S. |
collection | PubMed |
description | Lipid metabolism in the liver is complex and involves the synthesis and secretion of very low density lipoproteins (VLDL), ketone bodies, and high rates of fatty acid oxidation, synthesis, and esterification. Exercise training induces several changes in lipid metabolism in the liver and affects VLDL secretion and fatty acid oxidation. These alterations are even more conspicuous in disease, as in obesity, and cancer cachexia. Our understanding of the mechanisms leading to metabolic adaptations in the liver as induced by exercise training has advanced considerably in the recent years, but much remains to be addressed. More recently, the adoption of high intensity exercise training has been put forward as a means of modulating hepatic metabolism. The purpose of the present paper is to summarise and discuss the merit of such new knowledge. |
format | Online Article Text |
id | pubmed-3321535 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-33215352012-04-27 Exercise Intensity Modulation of Hepatic Lipid Metabolism Lira, Fábio S. Carnevali, Luiz C. Zanchi, Nelo E. Santos, Ronaldo VT. Lavoie, Jean Marc Seelaender, Marília J Nutr Metab Review Article Lipid metabolism in the liver is complex and involves the synthesis and secretion of very low density lipoproteins (VLDL), ketone bodies, and high rates of fatty acid oxidation, synthesis, and esterification. Exercise training induces several changes in lipid metabolism in the liver and affects VLDL secretion and fatty acid oxidation. These alterations are even more conspicuous in disease, as in obesity, and cancer cachexia. Our understanding of the mechanisms leading to metabolic adaptations in the liver as induced by exercise training has advanced considerably in the recent years, but much remains to be addressed. More recently, the adoption of high intensity exercise training has been put forward as a means of modulating hepatic metabolism. The purpose of the present paper is to summarise and discuss the merit of such new knowledge. Hindawi Publishing Corporation 2012 2012-04-02 /pmc/articles/PMC3321535/ /pubmed/22545209 http://dx.doi.org/10.1155/2012/809576 Text en Copyright © 2012 Fábio S. Lira et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Article Lira, Fábio S. Carnevali, Luiz C. Zanchi, Nelo E. Santos, Ronaldo VT. Lavoie, Jean Marc Seelaender, Marília Exercise Intensity Modulation of Hepatic Lipid Metabolism |
title | Exercise Intensity Modulation of Hepatic Lipid Metabolism |
title_full | Exercise Intensity Modulation of Hepatic Lipid Metabolism |
title_fullStr | Exercise Intensity Modulation of Hepatic Lipid Metabolism |
title_full_unstemmed | Exercise Intensity Modulation of Hepatic Lipid Metabolism |
title_short | Exercise Intensity Modulation of Hepatic Lipid Metabolism |
title_sort | exercise intensity modulation of hepatic lipid metabolism |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3321535/ https://www.ncbi.nlm.nih.gov/pubmed/22545209 http://dx.doi.org/10.1155/2012/809576 |
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