Determination of RET Sequence Variation in an MEN2 Unaffected Cohort Using Multiple-Sample Pooling and Next-Generation Sequencing

Multisample, nonindexed pooling combined with next-generation sequencing (NGS) was used to discover RET proto-oncogene sequence variation within a cohort known to be unaffected by multiple endocrine neoplasia type 2 (MEN2). DNA samples (113 Caucasians, 23 persons of other ethnicities) were amplified...

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Detalles Bibliográficos
Autores principales: Margraf, R. L., Durtschi, J. D., Stephens, J. E., Perez, M., Voelkerding, K. V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3321559/
https://www.ncbi.nlm.nih.gov/pubmed/22545224
http://dx.doi.org/10.1155/2012/318232

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3321559/
https://www.ncbi.nlm.nih.gov/pubmed/22545224
http://dx.doi.org/10.1155/2012/318232

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