Cargando…

Human embryonic stem cell derived astrocytes mediate non-cell-autonomous neuroprotection through endogenous and drug-induced mechanisms

The glial environment is an important determinant of neuronal health in experimental models of neurodegeneration. Specifically, astrocytes have been shown, dependent on context, to be both injurious and protective. Human pluripotent stem cells offer a powerful new system to improve our understanding...

Descripción completa

Detalles Bibliográficos
Autores principales: Gupta, K, Patani, R, Baxter, P, Serio, A, Story, D, Tsujita, T, Hayes, J D, Pedersen, R A, Hardingham, G E, Chandran, S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3321621/
https://www.ncbi.nlm.nih.gov/pubmed/22095276
http://dx.doi.org/10.1038/cdd.2011.154