Postexposure Treatment of Marburg Virus Infection

Rhesus monkeys are protected from disease when a recombinant vesicular stomatitis virus–based vaccine is administered 20–30 min after infection with Marburg virus. We protected 5/6 monkeys when this vaccine was given 24 h after challenge; 2/6 animals were protected when the vaccine was administered...

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Detalles Bibliográficos
Autores principales: Geisbert, Thomas W., Hensley, Lisa E., Geisbert, Joan B., Leung, Anders, Johnson, Joshua C., Grolla, Allen, Feldmann, Heinz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2010
Materias:
Dispatch
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3321919/
https://www.ncbi.nlm.nih.gov/pubmed/20587184
http://dx.doi.org/10.3201/eid1607.100159
Descripción
Sumario:Rhesus monkeys are protected from disease when a recombinant vesicular stomatitis virus–based vaccine is administered 20–30 min after infection with Marburg virus. We protected 5/6 monkeys when this vaccine was given 24 h after challenge; 2/6 animals were protected when the vaccine was administered 48 h postinfection.

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