Postexposure Treatment of Marburg Virus Infection

Rhesus monkeys are protected from disease when a recombinant vesicular stomatitis virus–based vaccine is administered 20–30 min after infection with Marburg virus. We protected 5/6 monkeys when this vaccine was given 24 h after challenge; 2/6 animals were protected when the vaccine was administered...

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Detalles Bibliográficos
Autores principales: Geisbert, Thomas W., Hensley, Lisa E., Geisbert, Joan B., Leung, Anders, Johnson, Joshua C., Grolla, Allen, Feldmann, Heinz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2010
Materias:
Dispatch
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3321919/
https://www.ncbi.nlm.nih.gov/pubmed/20587184
http://dx.doi.org/10.3201/eid1607.100159
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author Geisbert, Thomas W.
Hensley, Lisa E.
Geisbert, Joan B.
Leung, Anders
Johnson, Joshua C.
Grolla, Allen
Feldmann, Heinz
author_facet Geisbert, Thomas W.
Hensley, Lisa E.
Geisbert, Joan B.
Leung, Anders
Johnson, Joshua C.
Grolla, Allen
Feldmann, Heinz
author_sort Geisbert, Thomas W.
collection PubMed
description Rhesus monkeys are protected from disease when a recombinant vesicular stomatitis virus–based vaccine is administered 20–30 min after infection with Marburg virus. We protected 5/6 monkeys when this vaccine was given 24 h after challenge; 2/6 animals were protected when the vaccine was administered 48 h postinfection.
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spelling pubmed-33219192012-04-24 Postexposure Treatment of Marburg Virus Infection Geisbert, Thomas W. Hensley, Lisa E. Geisbert, Joan B. Leung, Anders Johnson, Joshua C. Grolla, Allen Feldmann, Heinz Emerg Infect Dis Dispatch Rhesus monkeys are protected from disease when a recombinant vesicular stomatitis virus–based vaccine is administered 20–30 min after infection with Marburg virus. We protected 5/6 monkeys when this vaccine was given 24 h after challenge; 2/6 animals were protected when the vaccine was administered 48 h postinfection. Centers for Disease Control and Prevention 2010-07 /pmc/articles/PMC3321919/ /pubmed/20587184 http://dx.doi.org/10.3201/eid1607.100159 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Dispatch
Geisbert, Thomas W.
Hensley, Lisa E.
Geisbert, Joan B.
Leung, Anders
Johnson, Joshua C.
Grolla, Allen
Feldmann, Heinz
Postexposure Treatment of Marburg Virus Infection
title Postexposure Treatment of Marburg Virus Infection
title_full Postexposure Treatment of Marburg Virus Infection
title_fullStr Postexposure Treatment of Marburg Virus Infection
title_full_unstemmed Postexposure Treatment of Marburg Virus Infection
title_short Postexposure Treatment of Marburg Virus Infection
title_sort postexposure treatment of marburg virus infection
topic Dispatch
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3321919/
https://www.ncbi.nlm.nih.gov/pubmed/20587184
http://dx.doi.org/10.3201/eid1607.100159
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