Contribution of Streptococcus anginosus to Infections Caused by Groups C and G Streptococci, Southern India

Vellore, a region in southern India, has a high incidence of severe human infections with β-hemolytic group C and G streptococci (GCGS). To determine the causative species in these infections, we conducted 16S rRNA gene sequencing: Streptococcus dysgalactiae subsp. equisimilis (81%) and S. anginosus...

Descripción completa

Detalles Bibliográficos
Autores principales: Reißmann, Silvana, Friedrichs, Claudia, Rajkumari, Reena, Itzek, Andreas, Fulde, Marcus, Rodloff, Arne C., Brahmadathan, Kootallur N., Chhatwal, Gursharan S., Nitsche-Schmitz, D. Patric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2010
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3321935/
https://www.ncbi.nlm.nih.gov/pubmed/20350380
http://dx.doi.org/10.3201/eid1604.090448
Descripción
Sumario:Vellore, a region in southern India, has a high incidence of severe human infections with β-hemolytic group C and G streptococci (GCGS). To determine the causative species in these infections, we conducted 16S rRNA gene sequencing: Streptococcus dysgalactiae subsp. equisimilis (81%) and S. anginosus (19%) were the causative organisms in the 2-year study period (2006–2007). We used PCR to detect the virulence-related emm gene; results showed that it was restricted to S. dysgalactieae subsp. equisimilis isolates of 99.2% tested positive. Due to a novel marker, S. anginosus and S. constellatus can be quickly and accurately distinguished from other members of the genus. The notable contribution of the anginosus group to human infections suggests that this group of obligate pathogens deserves more attention in healthcare and research.

Ejemplares similares