Contribution of Streptococcus anginosus to Infections Caused by Groups C and G Streptococci, Southern India

Vellore, a region in southern India, has a high incidence of severe human infections with β-hemolytic group C and G streptococci (GCGS). To determine the causative species in these infections, we conducted 16S rRNA gene sequencing: Streptococcus dysgalactiae subsp. equisimilis (81%) and S. anginosus...

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Autores principales: Reißmann, Silvana, Friedrichs, Claudia, Rajkumari, Reena, Itzek, Andreas, Fulde, Marcus, Rodloff, Arne C., Brahmadathan, Kootallur N., Chhatwal, Gursharan S., Nitsche-Schmitz, D. Patric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2010
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3321935/
https://www.ncbi.nlm.nih.gov/pubmed/20350380
http://dx.doi.org/10.3201/eid1604.090448
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author Reißmann, Silvana
Friedrichs, Claudia
Rajkumari, Reena
Itzek, Andreas
Fulde, Marcus
Rodloff, Arne C.
Brahmadathan, Kootallur N.
Chhatwal, Gursharan S.
Nitsche-Schmitz, D. Patric
author_facet Reißmann, Silvana
Friedrichs, Claudia
Rajkumari, Reena
Itzek, Andreas
Fulde, Marcus
Rodloff, Arne C.
Brahmadathan, Kootallur N.
Chhatwal, Gursharan S.
Nitsche-Schmitz, D. Patric
author_sort Reißmann, Silvana
collection PubMed
description Vellore, a region in southern India, has a high incidence of severe human infections with β-hemolytic group C and G streptococci (GCGS). To determine the causative species in these infections, we conducted 16S rRNA gene sequencing: Streptococcus dysgalactiae subsp. equisimilis (81%) and S. anginosus (19%) were the causative organisms in the 2-year study period (2006–2007). We used PCR to detect the virulence-related emm gene; results showed that it was restricted to S. dysgalactieae subsp. equisimilis isolates of 99.2% tested positive. Due to a novel marker, S. anginosus and S. constellatus can be quickly and accurately distinguished from other members of the genus. The notable contribution of the anginosus group to human infections suggests that this group of obligate pathogens deserves more attention in healthcare and research.
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spelling pubmed-33219352012-04-24 Contribution of Streptococcus anginosus to Infections Caused by Groups C and G Streptococci, Southern India Reißmann, Silvana Friedrichs, Claudia Rajkumari, Reena Itzek, Andreas Fulde, Marcus Rodloff, Arne C. Brahmadathan, Kootallur N. Chhatwal, Gursharan S. Nitsche-Schmitz, D. Patric Emerg Infect Dis Research Vellore, a region in southern India, has a high incidence of severe human infections with β-hemolytic group C and G streptococci (GCGS). To determine the causative species in these infections, we conducted 16S rRNA gene sequencing: Streptococcus dysgalactiae subsp. equisimilis (81%) and S. anginosus (19%) were the causative organisms in the 2-year study period (2006–2007). We used PCR to detect the virulence-related emm gene; results showed that it was restricted to S. dysgalactieae subsp. equisimilis isolates of 99.2% tested positive. Due to a novel marker, S. anginosus and S. constellatus can be quickly and accurately distinguished from other members of the genus. The notable contribution of the anginosus group to human infections suggests that this group of obligate pathogens deserves more attention in healthcare and research. Centers for Disease Control and Prevention 2010-04 /pmc/articles/PMC3321935/ /pubmed/20350380 http://dx.doi.org/10.3201/eid1604.090448 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Research
Reißmann, Silvana
Friedrichs, Claudia
Rajkumari, Reena
Itzek, Andreas
Fulde, Marcus
Rodloff, Arne C.
Brahmadathan, Kootallur N.
Chhatwal, Gursharan S.
Nitsche-Schmitz, D. Patric
Contribution of Streptococcus anginosus to Infections Caused by Groups C and G Streptococci, Southern India
title Contribution of Streptococcus anginosus to Infections Caused by Groups C and G Streptococci, Southern India
title_full Contribution of Streptococcus anginosus to Infections Caused by Groups C and G Streptococci, Southern India
title_fullStr Contribution of Streptococcus anginosus to Infections Caused by Groups C and G Streptococci, Southern India
title_full_unstemmed Contribution of Streptococcus anginosus to Infections Caused by Groups C and G Streptococci, Southern India
title_short Contribution of Streptococcus anginosus to Infections Caused by Groups C and G Streptococci, Southern India
title_sort contribution of streptococcus anginosus to infections caused by groups c and g streptococci, southern india
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3321935/
https://www.ncbi.nlm.nih.gov/pubmed/20350380
http://dx.doi.org/10.3201/eid1604.090448
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