Fluoroquinolone Resistance and Clostridium difficile, Germany

We characterized 670 Clostridium difficile isolates collected from patients in 84 hospitals in Germany in 2008. PCR ribotyping showed high prevalence of ribotype 001 and restricted dissemination of ribotype 027 strains. Fluoroquinolone resistance and associated gyrase mutations were frequent in vari...

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Autores principales: Zaiß, Nils Henning, Witte, Wolfgang, Nübel, Ulrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2010
Materias:
Dispatch
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3321944/
https://www.ncbi.nlm.nih.gov/pubmed/20350385
http://dx.doi.org/10.3201/eid1604.090859
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author Zaiß, Nils Henning
Witte, Wolfgang
Nübel, Ulrich
author_facet Zaiß, Nils Henning
Witte, Wolfgang
Nübel, Ulrich
author_sort Zaiß, Nils Henning
collection PubMed
description We characterized 670 Clostridium difficile isolates collected from patients in 84 hospitals in Germany in 2008. PCR ribotyping showed high prevalence of ribotype 001 and restricted dissemination of ribotype 027 strains. Fluoroquinolone resistance and associated gyrase mutations were frequent in various ribotypes, but no resistance to metronidazole or vancomycin was noted.
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spelling pubmed-33219442012-04-24 Fluoroquinolone Resistance and Clostridium difficile, Germany Zaiß, Nils Henning Witte, Wolfgang Nübel, Ulrich Emerg Infect Dis Dispatch We characterized 670 Clostridium difficile isolates collected from patients in 84 hospitals in Germany in 2008. PCR ribotyping showed high prevalence of ribotype 001 and restricted dissemination of ribotype 027 strains. Fluoroquinolone resistance and associated gyrase mutations were frequent in various ribotypes, but no resistance to metronidazole or vancomycin was noted. Centers for Disease Control and Prevention 2010-04 /pmc/articles/PMC3321944/ /pubmed/20350385 http://dx.doi.org/10.3201/eid1604.090859 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Dispatch
Zaiß, Nils Henning
Witte, Wolfgang
Nübel, Ulrich
Fluoroquinolone Resistance and Clostridium difficile, Germany
title Fluoroquinolone Resistance and Clostridium difficile, Germany
title_full Fluoroquinolone Resistance and Clostridium difficile, Germany
title_fullStr Fluoroquinolone Resistance and Clostridium difficile, Germany
title_full_unstemmed Fluoroquinolone Resistance and Clostridium difficile, Germany
title_short Fluoroquinolone Resistance and Clostridium difficile, Germany
title_sort fluoroquinolone resistance and clostridium difficile, germany
topic Dispatch
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3321944/
https://www.ncbi.nlm.nih.gov/pubmed/20350385
http://dx.doi.org/10.3201/eid1604.090859
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