Experimental Infection of Squirrel Monkeys with Nipah Virus

We infected squirrel monkeys (Saimiri sciureus) with Nipah virus to determine the monkeys’ suitability for use as primate models in preclinical testing of preventive and therapeutic treatments. Infection of squirrel monkeys through intravenous injection was followed by high death rates associated wi...

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Detalles Bibliográficos
Autores principales: Marianneau, Philippe, Guillaume, Vanessa, Wong, K. Thong, Badmanathan, Munisamy, Looi, Ren Yih, Murri, Séverine, Loth, Philippe, Tordo, Noël, Wild, T. Fabian, Horvat, Branka, Contamin, Hugues
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2010
Materias:
Dispatch
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3322034/
https://www.ncbi.nlm.nih.gov/pubmed/20202432
http://dx.doi.org/10.3201/eid1603.091346
Descripción
Sumario:We infected squirrel monkeys (Saimiri sciureus) with Nipah virus to determine the monkeys’ suitability for use as primate models in preclinical testing of preventive and therapeutic treatments. Infection of squirrel monkeys through intravenous injection was followed by high death rates associated with acute neurologic and respiratory illness and viral RNA and antigen production.

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