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Geographic Distribution of Endemic Fungal Infections among Older Persons, United States

To investigate the epidemiology and geographic distribution of histoplasmosis, coccidioidomycosis, and blastomycosis in older persons in the United States, we evaluated a random 5% sample of national Medicare data from 1999 through 2008. We calculated national, regional, and state-based incidence ra...

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Autores principales: Baddley, John W., Winthrop, Kevin L., Patkar, Nivedita M., Delzell, Elizabeth, Beukelman, Timothy, Xie, Fenglong, Chen, Lang, Curtis, Jeffrey R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3322071/
https://www.ncbi.nlm.nih.gov/pubmed/21888792
http://dx.doi.org/10.3201/eid1709.101987
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author Baddley, John W.
Winthrop, Kevin L.
Patkar, Nivedita M.
Delzell, Elizabeth
Beukelman, Timothy
Xie, Fenglong
Chen, Lang
Curtis, Jeffrey R.
author_facet Baddley, John W.
Winthrop, Kevin L.
Patkar, Nivedita M.
Delzell, Elizabeth
Beukelman, Timothy
Xie, Fenglong
Chen, Lang
Curtis, Jeffrey R.
author_sort Baddley, John W.
collection PubMed
description To investigate the epidemiology and geographic distribution of histoplasmosis, coccidioidomycosis, and blastomycosis in older persons in the United States, we evaluated a random 5% sample of national Medicare data from 1999 through 2008. We calculated national, regional, and state-based incidence rates and determined 90-day postdiagnosis mortality rates. We identified 776 cases (357 histoplasmosis, 345 coccidioidomycosis, 74 blastomycosis). Patient mean age was 75.7 years; 55% were male. Histoplasmosis and blastomycosis incidence was highest in the Midwest (6.1 and 1.0 cases/100,000 person-years, respectively); coccidioidomycosis incidence rate was highest in the West (15.2). On the basis of available data, for 86 (11.1%) cases, there was no patient exposure to a traditional disease-endemic area. Knowledge of areas where endemic mycosis incidence is increased may affect diagnostic or prevention measures for older adults at risk.
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spelling pubmed-33220712012-04-30 Geographic Distribution of Endemic Fungal Infections among Older Persons, United States Baddley, John W. Winthrop, Kevin L. Patkar, Nivedita M. Delzell, Elizabeth Beukelman, Timothy Xie, Fenglong Chen, Lang Curtis, Jeffrey R. Emerg Infect Dis Research To investigate the epidemiology and geographic distribution of histoplasmosis, coccidioidomycosis, and blastomycosis in older persons in the United States, we evaluated a random 5% sample of national Medicare data from 1999 through 2008. We calculated national, regional, and state-based incidence rates and determined 90-day postdiagnosis mortality rates. We identified 776 cases (357 histoplasmosis, 345 coccidioidomycosis, 74 blastomycosis). Patient mean age was 75.7 years; 55% were male. Histoplasmosis and blastomycosis incidence was highest in the Midwest (6.1 and 1.0 cases/100,000 person-years, respectively); coccidioidomycosis incidence rate was highest in the West (15.2). On the basis of available data, for 86 (11.1%) cases, there was no patient exposure to a traditional disease-endemic area. Knowledge of areas where endemic mycosis incidence is increased may affect diagnostic or prevention measures for older adults at risk. Centers for Disease Control and Prevention 2011-09 /pmc/articles/PMC3322071/ /pubmed/21888792 http://dx.doi.org/10.3201/eid1709.101987 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Research
Baddley, John W.
Winthrop, Kevin L.
Patkar, Nivedita M.
Delzell, Elizabeth
Beukelman, Timothy
Xie, Fenglong
Chen, Lang
Curtis, Jeffrey R.
Geographic Distribution of Endemic Fungal Infections among Older Persons, United States
title Geographic Distribution of Endemic Fungal Infections among Older Persons, United States
title_full Geographic Distribution of Endemic Fungal Infections among Older Persons, United States
title_fullStr Geographic Distribution of Endemic Fungal Infections among Older Persons, United States
title_full_unstemmed Geographic Distribution of Endemic Fungal Infections among Older Persons, United States
title_short Geographic Distribution of Endemic Fungal Infections among Older Persons, United States
title_sort geographic distribution of endemic fungal infections among older persons, united states
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3322071/
https://www.ncbi.nlm.nih.gov/pubmed/21888792
http://dx.doi.org/10.3201/eid1709.101987
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