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Recombinant Human Endostatin Normalizes Tumor Vasculature and Enhances Radiation Response in Xenografted Human Nasopharyngeal Carcinoma Models

BACKGROUND: Hypoxic tumor cells can reduce the efficacy of radiation. Antiangiogenic therapy may transiently “normalize” the tumor vasculature to make it more efficient for oxygen delivery. The aim of this study is to investigate whether the recombinant human endostatin (endostar) can create a “vasc...

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Detalles Bibliográficos
Autores principales:	Peng, Fang, Xu, Zumin, Wang, Jin, Chen, Yuanyuan, Li, Qiang, Zuo, Yufang, Chen, Jing, Hu, Xiao, Zhou, Qichao, Wang, Yan, Ma, Honglian, Bao, Yong, Chen, Ming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3322143/ https://www.ncbi.nlm.nih.gov/pubmed/22496834 http://dx.doi.org/10.1371/journal.pone.0034646

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