Direct Observation of Strand Passage by DNA-Topoisomerase and Its Limited Processivity

Type-II DNA topoisomerases resolve DNA entanglements such as supercoils, knots and catenanes by passing one segment of DNA duplex through a transient enzyme-bridged double-stranded break in another segment. The ATP-dependent passage reaction has previously been demonstrated at the single-molecule le...

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Detalles Bibliográficos
Autores principales: Yogo, Katsunori, Ogawa, Taisaku, Hayashi, Masahito, Harada, Yoshie, Nishizaka, Takayuki, Kinosita, Kazuhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3322154/
https://www.ncbi.nlm.nih.gov/pubmed/22496876
http://dx.doi.org/10.1371/journal.pone.0034920

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3322154/
https://www.ncbi.nlm.nih.gov/pubmed/22496876
http://dx.doi.org/10.1371/journal.pone.0034920

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