RAGE Mediates Accelerated Diabetic Vein Graft Atherosclerosis Induced by Combined Mechanical Stress and AGEs via Synergistic ERK Activation

AIMS/HYPOTHESIS: Diabetes with hypertension rapidly accelerates vascular disease, but the underlying mechanism remains unclear. We evaluated the hypothesis that the receptor of advanced glycation end products (RAGE) might mediate combined signals initiated by diabetes-related AGEs and hypertension-i...

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Detalles Bibliográficos
Autores principales: Li, Yuhuang, Liu, Shuying, Zhang, Zhengyu, Xu, Qingbo, Xie, Fukang, Wang, Jingjing, Ping, Suning, Li, Chen, Wang, Zhaojing, Zhang, Min, Huang, Jintao, Chen, Dadi, Hu, Liping, Li, Chaohong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3322163/
https://www.ncbi.nlm.nih.gov/pubmed/22496883
http://dx.doi.org/10.1371/journal.pone.0035016

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