A Facile Synthesis of New 2-Amino-4H-pyran-3-carbonitriles by a One-Pot Reaction of α, α′-Bis(arylidene) Cycloalkanones and Malononitrile in the Presence of K(2)CO(3)

A rapid and environmentally friendly method is developed for the synthesis of a series of new substituted 2-amino-4H-pyran-3-carbonitriles through a one-pot condensation of malononitrile and α, α′-bis(arylidene) cycloalkanones in ethanol by using K(2)CO(3) as a catalyst. Short experimental reaction...

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Detalles Bibliográficos
Autores principales: Karimi-Jaberi, Zahed, Pooladian, Baharak
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Scientific World Journal 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3322370/
https://www.ncbi.nlm.nih.gov/pubmed/22545011
http://dx.doi.org/10.1100/2012/208796
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author Karimi-Jaberi, Zahed
Pooladian, Baharak
author_facet Karimi-Jaberi, Zahed
Pooladian, Baharak
author_sort Karimi-Jaberi, Zahed
collection PubMed
description A rapid and environmentally friendly method is developed for the synthesis of a series of new substituted 2-amino-4H-pyran-3-carbonitriles through a one-pot condensation of malononitrile and α, α′-bis(arylidene) cycloalkanones in ethanol by using K(2)CO(3) as a catalyst. Short experimental reaction times, excellent yields, no need to use cumbersome apparatus for purification of the products, and inexpensiveness and commercially availability of the catalyst are the advantages of this method.
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spelling pubmed-33223702012-04-27 A Facile Synthesis of New 2-Amino-4H-pyran-3-carbonitriles by a One-Pot Reaction of α, α′-Bis(arylidene) Cycloalkanones and Malononitrile in the Presence of K(2)CO(3) Karimi-Jaberi, Zahed Pooladian, Baharak ScientificWorldJournal Research Article A rapid and environmentally friendly method is developed for the synthesis of a series of new substituted 2-amino-4H-pyran-3-carbonitriles through a one-pot condensation of malononitrile and α, α′-bis(arylidene) cycloalkanones in ethanol by using K(2)CO(3) as a catalyst. Short experimental reaction times, excellent yields, no need to use cumbersome apparatus for purification of the products, and inexpensiveness and commercially availability of the catalyst are the advantages of this method. The Scientific World Journal 2012-04-01 /pmc/articles/PMC3322370/ /pubmed/22545011 http://dx.doi.org/10.1100/2012/208796 Text en Copyright © 2012 Z. Karimi-Jaberi and B. Pooladian. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Karimi-Jaberi, Zahed
Pooladian, Baharak
A Facile Synthesis of New 2-Amino-4H-pyran-3-carbonitriles by a One-Pot Reaction of α, α′-Bis(arylidene) Cycloalkanones and Malononitrile in the Presence of K(2)CO(3)
title A Facile Synthesis of New 2-Amino-4H-pyran-3-carbonitriles by a One-Pot Reaction of α, α′-Bis(arylidene) Cycloalkanones and Malononitrile in the Presence of K(2)CO(3)
title_full A Facile Synthesis of New 2-Amino-4H-pyran-3-carbonitriles by a One-Pot Reaction of α, α′-Bis(arylidene) Cycloalkanones and Malononitrile in the Presence of K(2)CO(3)
title_fullStr A Facile Synthesis of New 2-Amino-4H-pyran-3-carbonitriles by a One-Pot Reaction of α, α′-Bis(arylidene) Cycloalkanones and Malononitrile in the Presence of K(2)CO(3)
title_full_unstemmed A Facile Synthesis of New 2-Amino-4H-pyran-3-carbonitriles by a One-Pot Reaction of α, α′-Bis(arylidene) Cycloalkanones and Malononitrile in the Presence of K(2)CO(3)
title_short A Facile Synthesis of New 2-Amino-4H-pyran-3-carbonitriles by a One-Pot Reaction of α, α′-Bis(arylidene) Cycloalkanones and Malononitrile in the Presence of K(2)CO(3)
title_sort facile synthesis of new 2-amino-4h-pyran-3-carbonitriles by a one-pot reaction of α, α′-bis(arylidene) cycloalkanones and malononitrile in the presence of k(2)co(3)
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3322370/
https://www.ncbi.nlm.nih.gov/pubmed/22545011
http://dx.doi.org/10.1100/2012/208796
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