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Protein carbonylation and aggregation precede neuronal apoptosis induced by partial glutathione depletion
While the build-up of oxidized proteins within cells is believed to be toxic, there is currently no evidence linking protein carbonylation and cell death. In the present study, we show that incubation of nPC12 (neuron-like PC12) cells with 50 μM DEM (diethyl maleate) leads to a partial and transient...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society for Neurochemistry
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3322383/ https://www.ncbi.nlm.nih.gov/pubmed/22376187 http://dx.doi.org/10.1042/AN20110064 |