Cargando…
A comprehensive survey of genomic alterations in gastric cancer reveals systematic patterns of molecular exclusivity and co-occurrence among distinct therapeutic targets
OBJECTIVE: Gastric cancer is a major gastrointestinal malignancy for which targeted therapies are emerging as treatment options. This study sought to identify the most prevalent molecular targets in gastric cancer and to elucidate systematic patterns of exclusivity and co-occurrence among these targ...
Autores principales: | Deng, Niantao, Goh, Liang Kee, Wang, Hannah, Das, Kakoli, Tao, Jiong, Tan, Iain Beehuat, Zhang, Shenli, Lee, Minghui, Wu, Jeanie, Lim, Kiat Hon, Lei, Zhengdeng, Goh, Glenn, Lim, Qing-Yan, Tan, Angie Lay-Keng, Sin Poh, Dianne Yu, Riahi, Sudep, Bell, Sandra, Shi, Michael M, Linnartz, Ronald, Zhu, Feng, Yeoh, Khay Guan, Toh, Han Chong, Yong, Wei Peng, Cheong, Hyun Cheol, Rha, Sun Young, Boussioutas, Alex, Grabsch, Heike, Rozen, Steve, Tan, Patrick |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Group
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3322587/ https://www.ncbi.nlm.nih.gov/pubmed/22315472 http://dx.doi.org/10.1136/gutjnl-2011-301839 |
Ejemplares similares
-
Signatures of tumour immunity distinguish Asian and non-Asian gastric adenocarcinomas
por: Lin, Suling J, et al.
Publicado: (2015) -
Machine-learning model derived gene signature predictive of paclitaxel survival benefit in gastric cancer: results from the randomised phase III SAMIT trial
por: Sundar, Raghav, et al.
Publicado: (2022) -
DNA damage signalling as an anti-cancer barrier in gastric intestinal metaplasia
por: Krishnan, Vaidehi, et al.
Publicado: (2020) -
OCT1 is a determinant of synbindin-related ERK signalling with independent prognostic significance in gastric cancer
por: Qian, Jin, et al.
Publicado: (2015) -
Epigenetic promoter alterations in GI tumour immune-editing and resistance to immune checkpoint inhibition
por: Sundar, Raghav, et al.
Publicado: (2022)