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Application of DEN refinement and automated model building to a difficult case of molecular-replacement phasing: the structure of a putative succinyl-diaminopimelate desuccinylase from Corynebacterium glutamicum
Phasing by molecular replacement remains difficult for targets that are far from the search model or in situations where the crystal diffracts only weakly or to low resolution. Here, the process of determining and refining the structure of Cgl1109, a putative succinyl-diaminopimelate desuccinylase f...
Autores principales: | Brunger, Axel T., Das, Debanu, Deacon, Ashley M., Grant, Joanna, Terwilliger, Thomas C., Read, Randy J., Adams, Paul D., Levitt, Michael, Schröder, Gunnar F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3322598/ https://www.ncbi.nlm.nih.gov/pubmed/22505259 http://dx.doi.org/10.1107/S090744491104978X |
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